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Home >> Antibodies >> TRPC6 Antibody

TRPC6 Antibody (R32851)

  Catalog No Formulation Size Price (USD)  
Image R32851 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 449
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Western blot testing of 1) rat ovary and 2) rat lung lysate with TRPC6 antibody at 0.5ug/ml. Predicted molecular weight ~106 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Predicted Reactivity Human
Format Antigen affinity purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt Q9Y210
Applications Western Blot : 0.5-1ug/ml
Limitations This TRPC6 antibody is available for research use only.
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Description

Transient receptor potential cation channel, subfamily C, member 6, also known as TRPC6, is a human gene encoding a protein of the same name. The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

Application Notes

Optimal dilution of the TRPC6 antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids K771-E875 was used as the immunogen for the TRPC6 antibody.

Storage

After reconstitution, the TRPC6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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