- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
TrkA Antibody / NTRK1 (F50683)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F50683-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F50683-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P04629 |
| Applications | Western blot : 1:1000 Flow Cytometry : 1:10-1:50 IHC (Paraffin) : 1:10-1:50 |
| Limitations | This TrkA antibody is available for research use only. |
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TRKA (also known as NTRK1) is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Titration of the TrkA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 769-796 from the human protein was used as the immunogen for this TrkA antibody.
Aliquot the TrkA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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