- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
TRIM29 Antibody Goat Polyclonal (R33820)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
R33820-100UG | 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide | 100 ug | 475 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat |
| Format | Antigen affinity purified |
| Host | Goat |
| Clonality | Polyclonal (goat origin) |
| Isotype | Goat Ig |
| Purity | Antigen affinity |
| Gene ID | 23650 |
| Applications | Western Blot : 0.3-1ug/ml Immunohistochemistry (FFPE) : 1-2ug/ml ELISA (peptide) LOD : 1:128000 |
| Limitations | This TRIM29 antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
Related Products
|
Tripartite motif containing 29 is a member of the TRIM protein family encoded by the TRIM29 gene and is also known as ataxia-telangiectasia group D complementing protein or ATDC. The TRIM29 Antibody Goat Polyclonal is designed to detect this cytoplasmic and nuclear protein in research applications focused on epithelial biology and tumor progression. TRIM29 is located on chromosome 11q23 and differs from many TRIM family members in that it lacks a canonical RING finger domain, while retaining B-box and coiled-coil structural motifs that contribute to protein-protein interactions.
TRIM29 functions as a regulatory scaffold protein and has been implicated in DNA damage response signaling, chromatin remodeling, and transcriptional control. It has been reported to interact with components of the p53 pathway and other signaling proteins that influence cellular responses to genotoxic stress. Through these mechanisms, TRIM29 contributes to regulation of cell proliferation, apoptosis, and epithelial differentiation. Subcellular localization studies describe both cytoplasmic and nuclear distribution, depending on cell type and physiologic context.
Expression of TRIM29 is enriched in epithelial tissues including pancreas, lung, breast, and gastrointestinal tract. In cancer research, altered TRIM29 expression has been observed in pancreatic, gastric, lung, and breast carcinomas. Its biological role appears context-dependent, with evidence supporting involvement in tumor progression, invasion, or modulation of stress signaling pathways depending on tumor type. These observations make TRIM29 a relevant target in studies examining epithelial transformation and oncogenic signaling networks.
As part of the broader tripartite motif family, TRIM29 participates in cellular pathways that regulate protein stability and stress adaptation. Investigation of TRIM29 expression supports research focused on epithelial integrity, DNA damage response mechanisms, and cancer-associated signaling pathways. The goat polyclonal TRIM29 antibody is suitable for detecting TRIM29 protein expression in diverse research settings.
Optimal dilution of the TRIM29 antibody should be determined by the researcher.
Amino acids EKDRIKSFTTNE were used as the immunogen for this goat polyclonal TRIM29 antibody.
Aliquot and store the TRIM29 antibody at -20oC.
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
