- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Transglutaminase 2 Antibody (R31273)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R31273 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal |
| UniProt | P21980 |
| Applications | Western blot : 0.5-1ug/ml IHC (FFPE) : 0.5-1ug/ml Immunocytochemistry : 0.5-1ug/ml |
| Limitations | This Transglutaminase 2 antibody is available for research use only. |
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Transglutaminase 2, also called TGC, TG2 and TGM2, is a 78-kDa, calcium dependent enzyme of the protein-glutamine gamma-glutamyltransferases family. Transglutaminases (TGs) are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of TGs are not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. Transglutaminase 2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It is the autoantigen implicated in celiac disease.
The stated application concentrations are suggested starting amounts. Titration of the Transglutaminase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the C-terminus of human TGM2 (ADVVDWIQQDDGSVHKSINR) was used as the immunogen for this Transglutaminase 2 antibody.
After reconstitution, the Transglutaminase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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