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Home >> Antibodies >> Transferrin Receptor Antibody / CD71

Transferrin Receptor Antibody / CD71 [clone TFRC/1059] (V2881)

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  Catalog No Formulation Size Price (USD)  
Image V2881-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V2881-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V2881SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Flow cytometry testing of human Jurkat cells with Transferrin Receptor antibody (clone TFRC/1059); Red=isotype control, Blue= Transferrin Receptor antibody.
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Flow cytometry testing of human Jurkat cells with Transferrin Receptor antibody (clone TFRC/1059); Red=isotype control, Blue= Transferrin Receptor antibody.
Flow cytometry testing of Jurkat cells. Black: cells alone; Grey: isotype control; Green: AF488-labeled Transferrin Receptor antibody (TFRC/1059).
Immunofluorescent staining of PFA-fixed human K562 cells with Transferrin Receptor antibody (clone TFRC/1059, green) and Reddot nuclear stain (red).
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name TFRC/1059
Purity Protein G affinity chromatography
UniProt P02786
Localization Cell surface
Applications Flow cytometry : 0.5-1ug/million cells
Immunofluorescence : 1-2ug/ml
Limitations This Transferrin Receptor antibody is available for research use only.
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Description

It recognizes a ~85-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Application Notes

Optimal dilution of the Transferrin Receptor antibody should be determined by the researcher.

Immunogen

Recombinant human protein was used as the immunogen for the Transferrin Receptor antibody.

Storage

Store the Transferrin Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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