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Home >> Antibodies >> Transferrin Receptor Antibody / CD71

Transferrin Receptor Antibody / CD71 [clone DF1513] (V2260)

  Catalog No Formulation Size Price (USD)  
Image V2260-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V2260-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V2260SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name DF1513
Purity Protein G affinity chromatography
Buffer 1X PBS, pH 7.4
Gene ID 7037
Localization Cell surface
Applications Flow cytometry : 0.5-1ug/10^6 cells
Immunofluorescence : 1-2ug/ml
Western blot : 0.5-1ug/ml
Limitations This Transferrin receptor antibody is available for research use only.
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Description

This antibody recognizes a ~85-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa (Workshop IV). The antibody is highly specific to transferrin receptor and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Application Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

Immunogen

The KG1 acute myeloid leukemia cell line was used as the immunogen for this Transferrin receptor antibody.

Storage

Store the Transferrin receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Alternate Names

Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR, Transferrin receptor antibody

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