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Home >> Antibodies >> TRAF4 Antibody

TRAF4 Antibody (R31116)

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  Catalog No Formulation Size Price (USD)  
Image R31116 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of TRAF4 antbody; Lane 1: rat thymus; 2: human HeLa; 3: (h) Jurkat; 4: mouse HEPA cell lysate. Predicted molecular weight: ~54 kDa.
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Western blot testing of TRAF4 antbody; Lane 1: rat thymus; 2: human HeLa; 3: (h) Jurkat; 4: mouse HEPA cell lysate. Predicted molecular weight: ~54 kDa.
IHC-P: TRAF4 antibody testing of human lung cancer tissue. HIER: steamed with pH6 citrate buffer.
IHC-P: TRAF4 antibody testing of rat lymphonodus tissue. HIER: steamed with pH6 citrate buffer.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q9BUZ4
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
Limitations This TRAF4 antibody is available for research use only.
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  • Applications : WB, ELISA
    Reactivity : Human
    Pred. Reactivity : Mouse

Description

TNF Receptor-Associated Factor 4, also called CART1 or MLN62, is a protein that in humans is encoded by the TRAF4 gene. It is a member of the TNF receptor associated factor (TRAF) family, a family of scaffold proteins. Tomasetto et al. (1995) identified genes that are overexpressed in breast cancer by differential screening of cDNAs from breast cancer-derived metastatic axillary lymph nodes. The TRAF4 cDNA, which they designated MLN62, was mapped to 17q11-q12 by radioisotopic in situ hybridization. To investigate the biologic function of TRAF4, Regnier et al. (2002) generated Traf4-deficient mice by gene disruption.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the TRAF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human TNF Receptor-Associated Factor 4 (PKFISHQDIRKRNYVRDD) was used as the immunogen for this TRAF4 antibody (100% homologous in human, mouse and rat).

Storage

After reconstitution, the TRAF4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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