- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
TPX2 Antibody / p100 [clone 1696CT464.66.9] (F53942)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F53942-0.2ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.2 ml | 399 | |
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F53942-0.05ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.05 ml | 185 |
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| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | 1696CT464.66.9 |
| Purity | Protein G affinity chromatography |
| UniProt | Q9ULW0 |
| Applications | Western blot : 1:1000-2000 |
| Limitations | This TPX2 antibody is available for research use only. |
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Targeting protein for Xklp2, also called TPX2 and p100, is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
Titration of the TPX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A partial recombinant protein corresponding to amino acids 1-531 from the human protein was used as the immunogen for the TPX2 antibody.
Aliquot the TPX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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