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Home >> Antibodies >> TOP1 Antibody / Topoisomerase I

TOP1 Antibody / Topoisomerase I [clone FIG-20] (RQ5363)

  Catalog No Formulation Size Price (USD)  
Image RQ5363 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
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Western blot testing of human Jurkat cell lysate with TOP1 antibody. Expected molecular weight: 91-100 kDa.
Availability 1-2 weeks
Species Reactivity Human, Mouse
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name FIG-20
Purity Affinity purified
UniProt P11387
Applications Western blot : 1:1000-1:2000
Limitations This TOP1 antibody is available for research use only.
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Description

The TOP1 gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [RefSeq]

Application Notes

Optimal dilution of the TOP1 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Topoisomerase I / TOP1 was used as the immunogen for the TOP1 antibody.

Storage

Store the TOP1 antibody at -20oC.

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