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Home >> Antibodies >> ABIN-1 Antibody / TNIP1

ABIN-1 Antibody / TNIP1 (RQ6402)

  Catalog No Formulation Size Price (USD)  
Image RQ6402 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 389
Western blot testing of human 1) HEK293, 2) Raji, 3) A549, 4) Caco-2, 5) T-47D, 6) rat spleen, 7) rat lung and 8) mouse lung tissue lysate with ABIN-1 antibody. Expected molecular weight: 72-85 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q15025
Localization Cytoplasmic, nuclear
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This ABIN-1 antibody is available for research use only.
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Description

TNFAIP3-interacting protein 1, also called ABIN-1 or A20-binding inhibitor of NF-kappa-B activation 1, is a protein that in humans is encoded by the TNIP1 gene. This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene.

Application Notes

Optimal dilution of the ABIN-1 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids E312-K371) was used as the immunogen for the ABIN-1 antibody.

Storage

After reconstitution, the ABIN-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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