Tissue Factor Antibody / CD142 [clone GGE-6] (RQ5414)

Tissue Factor Antibody Multi-Species WB. Western blot analysis of human, rat, and mouse lysates using Tissue Factor antibody. Lane 1: human SH-SY5Y lysate, Lane 2: human A549 lysate, Lane 3: human PANC-1 lysate, Lane 4: rat lung lysate, Lane 5: rat liver lysate, Lane 6: mouse lung lysate, Lane 7: mouse liver lysate. A predominant band is detected near 45-50 kDa, compared to the predicted molecular weight of Tissue Factor / F3 / CD142 at approximately 35 kDa. The higher apparent molecular weight is consistent with known glycosylation of this membrane-associated coagulation receptor, which can alter electrophoretic mobility during SDS-PAGE analysis. The observed expression pattern supports the role of Tissue Factor in coagulation pathway activation, inflammatory signaling, vascular injury response, and tumor-associated procoagulant activity across multiple mammalian tissues and cell types.

Tissue Factor Antibody Colon Cancer IHC. Immunohistochemistry analysis of FFPE human colon cancer tissue using Tissue Factor antibody. Tumor epithelial cells demonstrate membranous and cytoplasmic HRP-DAB brown staining consistent with the surface-associated localization of Tissue Factor / CD142 in coagulation signaling, inflammatory pathway activation, and tumor-associated procoagulant activity within colorectal carcinoma tissue. Nuclei are counterstained blue. Heat-induced epitope retrieval was performed using EDTA buffer, pH8.0, prior to staining.

Tissue Factor Antibody Lung Cancer IHC. Immunohistochemistry analysis of FFPE human lung cancer tissue using Tissue Factor antibody. Tumor epithelial cells demonstrate membranous and cytoplasmic HRP-DAB brown staining consistent with the surface-associated localization of Tissue Factor / F3 / CD142 in coagulation pathway activation, inflammatory signaling, and tumor-associated prothrombotic activity within pulmonary carcinoma tissue. Nuclei are counterstained blue. Heat-induced epitope retrieval was performed using EDTA buffer, pH8.0, prior to staining.