- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
TIMP2 Antibody [clone AADE-20] (RQ5461)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5461 | Antibody in PBS with 0.02% sodium azide and 50% glycerol | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | AADE-20 |
| Purity | Affinity purified |
| UniProt | P16035 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This TIMP2 antibody is available for research use only. |
|
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The TIMP2 gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [RefSeq]
Optimal dilution of the TIMP2 antibody should be determined by the researcher.
A synthetic peptide specific to human TIMP2 was used as the immunogen for the TIMP2 antibody.
Store the TIMP2 antibody at -20oC.
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