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Home >> Antibodies >> TIMP1 Antibody

TIMP1 Antibody [clone AAOD-20] (RQ4857)

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Image RQ4857 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
Microvalidated Rab Mono Image
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Western blot testing of human prostate cancer lysate with TIMP1 antibody. Expected molecular weight: 23-28 kDa depending on the level of glycosylation.
Western blot testing of human prostate cancer lysate with TIMP1 antibody. Expected molecular weight: 23-28 kDa depending on the level of glycosylation.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AAOD-20
Purity Affinity purified
UniProt P01033
Applications Western blot : 1:500-1:2000
Limitations This TIMP1 antibody is available for research use only.
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Description

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [RefSeq]

Application Notes

Optimal dilution of the TIMP1 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human TIMP1 was used as the immunogen for the TIMP1 antibody.

Storage

Store the TIMP1 antibody at -20oC.

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