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- Tel: 858.663.9055
- Email: info@nsjbio.com
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TIGIT (also called T cell immunoreceptor with Ig and ITIM domains) is an immune receptor present on some T cells and Natural Killer Cells (NK). This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Optimal dilution of the Tigit antibody should be determined by the researcher.
A mouse recombinant partial protein (amino acids T29-G249) was used as the immunogen for the Tigit antibody.
After reconstitution, the Tigit antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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