- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Titration of the TIGIT antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 12-142 from the human protein was used as the immunogen for this TIGIT antibody.
Aliquot the TIGIT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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