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Home >> Antibodies >> TIGIT Antibody / VSTM3 / VSIG9

TIGIT Antibody / VSTM3 / VSIG9 (F53798)

  Catalog No Formulation Size Price (USD)  
Image F53798-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F53798-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
Bulk quote request
Western blot testing of 1) mouse EL4, human 2) fetal thymus, 3) spleen, 4) HUT78, 5) Jurkat and 6) Molt-4 lysate with TIGIT antibody. Predicted molecular weight ~26 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q495A1
Applications Western blot : 1:2000
Limitations This TIGIT antibody is available for research use only.
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Description

TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Application Notes

Titration of the TIGIT antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 12-142 from the human protein was used as the immunogen for this TIGIT antibody.

Storage

Aliquot the TIGIT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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