- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Related Products
|
TGN46 Antibody / TGOLN2 recognizes trans-Golgi network integral membrane protein 2 (TGOLN2), a membrane-associated glycoprotein commonly referred to as TGN46. This protein is primarily localized to the trans-Golgi network, where it participates in intracellular protein trafficking, cargo sorting, vesicle transport, and maintenance of Golgi organization. The trans-Golgi network acts as a major sorting compartment responsible for directing newly processed proteins and lipids to the plasma membrane, secretory vesicles, and endosomal pathways. TGN46 Antibody / TGOLN2 is commonly used to study Golgi biology, secretory pathway regulation, and intracellular membrane trafficking.
TGN46 cycles between the trans-Golgi network, cell surface, and endosomal compartments, reflecting its role in dynamic membrane transport processes. The protein contains trafficking signals within its cytoplasmic domain that contribute to its localization and recycling. Because of its strong enrichment within the trans-Golgi network, TGN46 is frequently used as a marker for analyzing Golgi structure, organelle distribution, and changes in cellular transport pathways. This recombinant rabbit monoclonal TGN46 Antibody / TGOLN2 (clone AOHO-20) provides researchers with a consistent tool for detecting TGOLN2 expression and localization.
Studies involving TGN46 help researchers examine the organization and function of the Golgi apparatus, including protein modification, packaging, and secretion. Alterations in Golgi structure and vesicle trafficking can influence cellular signaling, immune responses, stress pathways, and disease-related processes. The mature TGOLN2/TGN46 protein is extensively glycosylated, which commonly results in slower migration during Western blot analysis compared with the predicted unmodified molecular weight.
For additional information about TGOLN2 biology, validated applications, and related products, learn more about our TGOLN2 Antibody, a Trans-Golgi Network Marker Antibody for studying Golgi organization, protein trafficking, vesicle transport, and secretory pathway regulation.
Optimal dilution of the TGN46 antibody should be determined by the researcher.
A synthetic peptide specific to human TGN46 / TGOLN2 was used as the immunogen for the TGN46 antibody.
Store the TGN46 antibody at -20oC.
TGOLN2 Antibody, Trans-Golgi Network Protein 2 Antibody, Trans-Golgi Network Integral Membrane Protein 2 Antibody, TGN38 Homolog Antibody, Golgi Marker Antibody, Trans-Golgi Marker Antibody
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.