- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
TG2 Antibody / Transglutaminase 2 (F50805)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F50805-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F50805-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | SAS immunoprecipitation purified |
| UniProt | P21980 |
| Applications | Western blot : 1:1000 |
| Limitations | This TG2 antibody is available for research use only. |
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Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.
Titration of the TG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 413-442 from the human protein was used as the immunogen for this TG2 antibody.
Aliquot the TG2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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