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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. [RefSeq]
Optimal dilution of the TG antibody should be determined by the researcher.
A synthetic peptide specific to human Thyroglobulin / TG was used as the immunogen for the TG antibody.
Store the TG antibody at -20oC.
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