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Home >> Antibodies >> Tenascin-R Antibody / TNR

Tenascin-R Antibody / TNR (RQ8849)

  Catalog No Formulation Size Price (USD)  
Image RQ8849 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 439
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Western blot testing of 1) rat brain and 2) mouse brain tissue lysate with Tenascin-R antibody. Predicted molecular weight: ~150 kDa, ~140 kDa (two isoforms), may be observed at higher molecular weights due to glycosylation.
Availability 1-2 days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity chromatography
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q92752
Applications Western Blot : 1-2ug/ml
ELISA : 0.1-0.5ug/ml
Limitations This Tenascin-R antibody is available for research use only.
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  • Applications : WB, IHC-P, FACS
    Reactivity : Human, Mouse, Rat

Description

Tenascin-R is a protein that in humans is encoded by the TNR gene. Tenascin-R (TNR) is an extracellular matrix protein expressed primarily in the central nervous system. It is a member of the tenascin(TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion), TNX (TNXB), and TNR. The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues. TNR has been detected predominantly in the central nervous system and is localized around motor neurons and on motor axons in the spinal cord, cerebellum, hippocampus, and olfactory bulb. It is suggested that tenascin-R has a role in initiating the detachment of neuroblasts from tangential chains and in initiating radial migration of the cells.

Application Notes

Optimal dilution of the Tenascin-R antibody should be determined by the researcher.

Immunogen

An E.coli-derived human recombinant protein (amino acids E60-R1007) was used as the immunogen for the Tenascin-R antibody.

Storage

After reconstitution, the Tenascin-R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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