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Home >> Antibodies >> Telomeric repeat-binding factor 1 Antibody / TRF1 / TERF1

Telomeric repeat-binding factor 1 Antibody / TRF1 / TERF1 (RQ6806)

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  Catalog No Formulation Size Price (USD)  
Image RQ6806 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Immunofluorescent staining of FFPE human A431 cells with Telomeric repeat-binding factor 1 antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
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Immunofluorescent staining of FFPE human A431 cells with Telomeric repeat-binding factor 1 antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
Western blot testing of human Jurkat cell lysate with Telomeric repeat-binding factor 1 antibody. Predicted molecular weight: 50-65 kDa depending on level of acetylation.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P54274
Localization Nuclear, cytoplasmic
Applications Western blot : 1-2ug/ml
Immunofluorescence : 1-2ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This Telomeric repeat-binding factor 1 antibody is available for research use only.
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Description

Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene. This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

Application Notes

Optimal dilution of the Telomeric repeat-binding factor 1 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids Q119-R341) was used as the immunogen for the Telomeric repeat-binding factor 1 antibody.

Storage

After reconstitution, the Telomeric repeat-binding factor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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