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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3 termini of DNA. The human TdT gene maps to chromosome 10q24.1 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. It is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.
Optimal dilution of the TdT antibody should be determined by the researcher.
A portion of amino acids 52-192 from the human protein was used as the immunogen for the TdT antibody.
Store the TdT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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