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Home >> Antibodies >> SUZ12 Antibody

SUZ12 Antibody (F53390)

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  Catalog No Formulation Size Price (USD)  
Image F53390-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F53390-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot testing of SUZ12 antibody at 1:2000 dilution. Lane 1: mouse spleen lysate; 2: F9 lysate; 3: HeLa lysate; Observed molecular weight 83~95 kDa.
Western blot testing of SUZ12 antibody at 1:2000 dilution. Lane 1: mouse spleen lysate; 2: F9 lysate; 3: HeLa lysate; Observed molecular weight 83~95 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q15022
Applications Western blot : 1:2000
Limitations This SUZ12 antibody is available for research use only.
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Description

Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Application Notes

Titration of the SUZ12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This SUZ12 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 375-408 amino acids from the Central region of human SUZ12.

Storage

Aliquot the SUZ12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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