- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
SUMO-activating enzyme subunit 1 Antibody / SAE1 (F54771)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54771-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F54771-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | Q9UBE0 |
| Localization | Nuclear, cytoplasmic |
| Applications | Western blot : 1:500-1:1000 Immunohistochemistry (FFPE) : 1:25 |
| Limitations | This SUMO-activating enzyme subunit 1 antibody is available for research use only. |
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The dimeric enzyme AOS1 acts as a an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2.
The stated application concentrations are suggested starting points. Titration of the SUMO-activating enzyme subunit 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 300-329 from the human protein was used as the immunogen for the SUMO-activating enzyme subunit 1 antibody.
Aliquot the SUMO-activating enzyme subunit 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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