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Home >> Antibodies >> SUMO-1 Antibody

SUMO-1 Antibody (F43187)

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  Catalog No Formulation Size Price (USD)  
Image F43187-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F43187-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Fluorescent image of A549 cell stained with SUMO-1 antibody at 1:25. SUMO1 immunoreactivity is localized to the nuclear membrane.
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Fluorescent image of A549 cell stained with SUMO-1 antibody at 1:25. SUMO1 immunoreactivity is localized to the nuclear membrane.
Western blot analysis of lysate from mouse Neuro-2a cell line using SUMO-1 antibody at 1:1000 for each lane. Predicted molecular weight: 12-15 kDa
SUMO-1 antibody western blot analysis in ZR-75-1 lysate
SUMO-1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat, Bovine, Pig
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P63165
Applications Western blot : 1:1000
Immunofluorescence : 1:10-1:50
IHC (Paraffin) : 1:10-1:50
Limitations This SUMO-1 antibody is available for research use only.
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Description

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Application Notes

Titration of the SUMO-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this SUMO-1 antibody.

Storage

Aliquot the SUMO-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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