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Home >> Antibodies >> SUMO-1 Antibody

SUMO-1 Antibody (F43187)

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  Catalog No Formulation Size Price (USD)  
Image F43187-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 439
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F43187-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 205
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Fluorescent image of A549 cell stained with SUMO-1 antibody at 1:25. SUMO1 immunoreactivity is localized to the nuclear membrane.
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Fluorescent image of A549 cell stained with SUMO-1 antibody at 1:25. SUMO1 immunoreactivity is localized to the nuclear membrane.
Western blot analysis of lysate from mouse Neuro-2a cell line using SUMO-1 antibody at 1:1000 for each lane. Predicted molecular weight: 12-15 kDa
SUMO-1 antibody western blot analysis in ZR-75-1 lysate
SUMO-1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat, Bovine, Pig
Format Antigen affinity purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P63165
Applications Western Blot : 1:1000
Immunofluorescence : 1:10-1:50
IHC (Paraffin) : 1:10-1:50
Limitations This SUMO-1 antibody is available for research use only.
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Description

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Application Notes

Titration of the SUMO-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this SUMO-1 antibody.

Storage

Aliquot the SUMO-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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