STAT1 Antibody (R32095)

Western blot testing of rat 1) testis, 2) brain, 3) liver, and human 4) placenta, 5) MCF7, and 6) SW620 lysate with STAT1 antibody. Predicted/observed molecular weight: ~91/84 kDa (alpha/beta).

STAT1 Antibody Breast Cancer IHC. Immunohistochemistry staining of FFPE human breast cancer tissue using STAT1 antibody demonstrates strong cytoplasmic and membranous staining within neoplastic epithelial cells, consistent with expression of Signal Transducer and Activator of Transcription 1 (STAT1). STAT1 is a key transcription factor within the JAK-STAT signaling pathway that mediates cellular responses to interferons, cytokines, and growth factor-associated signaling networks. The observed staining pattern is consistent with the role of STAT1 in regulating transcriptional programs involved in immune responses, cellular differentiation, signal transduction, and tumor-associated signaling pathways. These findings support the utility of STAT1 antibody for studies of cytokine signaling, transcription factor biology, and cancer-related cellular regulation. HIER: boil paraffin sections in pH 6 10mM citrate buffer for 20 minutes and allow to cool prior to staining.

STAT1 Antibody Mouse Intestine IHC. Immunohistochemistry staining of FFPE mouse intestine tissue using STAT1 antibody demonstrates prominent staining within intestinal epithelial cell populations, consistent with expression of Signal Transducer and Activator of Transcription 1 (STAT1). STAT1 is a central transcription factor within the JAK-STAT signaling pathway that mediates cellular responses to interferons, cytokines, and other extracellular signaling molecules. The observed staining pattern is consistent with the role of STAT1 in regulating immune signaling, epithelial homeostasis, and transcriptional responses to environmental and inflammatory stimuli within gastrointestinal tissues. These findings support the utility of STAT1 antibody for studies of signal transduction, cytokine-responsive pathways, and tissue-specific transcription factor expression. HIER: boil paraffin sections in pH 6 10mM citrate buffer for 20 minutes and allow to cool prior to staining.

STAT1 Antibody Rat Intestine IHC. Immunohistochemistry staining of FFPE rat intestine tissue using STAT1 antibody demonstrates distinct staining within intestinal epithelial and mucosal-associated cell populations, consistent with expression of Signal Transducer and Activator of Transcription 1 (STAT1). STAT1 is a key transcription factor within the JAK-STAT signaling pathway that mediates cellular responses to interferons, cytokines, and immune regulatory signals. The observed staining pattern is consistent with the role of STAT1 in regulating transcriptional programs involved in epithelial homeostasis, immune surveillance, and cytokine-responsive signaling within gastrointestinal tissues. These findings support the utility of STAT1 antibody for studies of signal transduction, immune regulation, and tissue-specific gene expression. HIER: boil paraffin sections in pH 6 10mM citrate buffer for 20 minutes and allow to cool prior to staining.