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Home >> Antibodies >> ST6GALNAC4 Antibody

ST6GALNAC4 Antibody (RQ7863)

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  Catalog No Formulation Size Price (USD)  
Image RQ7863 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) huma HeLa, 2) rat lung, 3) rat H9C2(2-1) and 4) mouse lung tissue lysate with ST6GALNAC4 antibody. Predicted molecular weight ~34 kDa.
Western blot testing of 1) huma HeLa, 2) rat lung, 3) rat H9C2(2-1) and 4) mouse lung tissue lysate with ST6GALNAC4 antibody. Predicted molecular weight ~34 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q9H4F1
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This ST6GALNAC4 antibody is available for research use only.
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Description

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4, also known as sialyltransferase 3C (SIAT3-C) or sialyltransferase 7D (SIAT7-D) is a sialyltransferase enzyme that in humans is encoded by the ST6GALNAC4 gene. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. Readthrough transcripts exist for this gene and the downstream ST6GALNAC6 gene.

Application Notes

Optimal dilution of the ST6GALNAC4 antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids D39-T302) was used as the immunogen for the ST6GALNAC4 antibody.

Storage

After reconstitution, the ST6GALNAC4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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