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Signal sequence receptor, gamma is also known as SSR3 and TRAPG. By immunoaffinity chromatography, biochemical purification, peptide sequence analysis, and screening of a rat liver cDNA library, Hartmann et al.(1993) obtained a cDNA encoding Ssr3, which they termed Trap-gamma. The deduced 185-amino acid protein spans the membrane 4 times and is expressed as a 20-kD protein. Gross(2012) mapped the SSR3 gene to chromosome 3q25.31 based on an alignment of the SSR3 sequence with the genomic sequence (GRCh37). Hartmann et al.(1993)found that Ssr3 was associated in equal amounts with Ssr1, Ssr2, and Ssr4 in canine pancreatic microsomes.
The stated application concentrations are suggested starting amounts. Titration of the SSR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Amino acids 8-23 (KQQSEEDLLLQDFSRN) were used as the immunogen for this SSR3 antibody (100% homologous in human, mouse and rat).
After reconstitution, the SSR3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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