- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
SRSF1 Antibody / SF2 (F54891)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54891-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F54891-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | Q07955 |
| Localization | Cytoplasmic |
| Applications | Flow cytometry : 1:10-1:50 (1x10e6 cells) Western blot : 1:500-1:1000 Immunohistochemistry (FFPE) : 1:50-1:100 |
| Limitations | This SRSF1 antibody is available for research use only. |
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SRSF1 is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins.
The stated application concentrations are suggested starting points. Titration of the SRSF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 158-186 from the human protein was used as the immunogen for the SRSF1 antibody.
Aliquot the SRSF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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