SRB1 Antibody / SCARB1 Antibody (R32260)

SRB1 Antibody Rat Adrenal Gland IHC. Immunohistochemical staining of FFPE rat adrenal gland demonstrated strong SRB1 expression with prominent membrane and cytoplasmic staining of adrenal cortical cells. Heat-induced epitope retrieval was performed in pH8 EDTA buffer before immunostaining with the primary antibody and HRP-DAB detection. The distribution is consistent with the role of SCARB1 in mediating HDL-derived cholesterol uptake for steroid hormone biosynthesis. This SRB1 Antibody, an SCARB1 Antibody, is suitable for immunohistochemical studies of cholesterol transport, adrenal physiology and steroidogenic tissues.

SRB1 Antibody Rat Adrenal Cortex IHC. Immunohistochemical staining of FFPE rat adrenal gland showed strong membrane and cytoplasmic SRB1 expression throughout the adrenal cortex, with minimal staining in surrounding stromal regions. Heat-induced epitope retrieval was performed in pH8 EDTA buffer prior to staining with HRP-DAB detection. The staining pattern is consistent with the high expression of SCARB1 in steroidogenic cells that utilize HDL-derived cholesterol for steroid hormone synthesis. This SRB1 Antibody, an SCARB1 Antibody, is well suited for immunohistochemical studies of adrenal steroidogenesis, cholesterol transport and endocrine tissue biology.

SRB1 Antibody Mouse and Rat Liver WB. Western blot analysis detected SRB1 in rat liver (lane 1) and mouse liver (lane 2), with a prominent immunoreactive band at approximately 75–80 kDa. Although the predicted molecular weight ranges from 57–82 kDa, depending on glycosylation, the observed migration is consistent with the mature glycosylated form of the receptor. This SRB1 Antibody, an SCARB1 Antibody, demonstrates cross-reactivity with both rat and mouse tissues and is well suited for studies of hepatic cholesterol uptake, HDL metabolism and lipid homeostasis.