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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Sepiapterin reductase is an enzyme that in humans is encoded by the SPR gene. This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Optimal dilution of the SPR antibody should be determined by the researcher.
A human partial recombinant protein corresponding to amino acids V36-K261 was used as the immunogen for the SPR antibody.
After reconstitution, the SPR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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