- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Titration of the SPR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 231-260 from the human protein was used as the immunogen for this SPR antibody.
Aliquot the SPR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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