- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Speedy protein A Antibody / SPDYA / Spy1 (F55052)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F55052-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F55052-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | Q5MJ70 |
| Localization | Predominantly nuclear, may show cytoplasmic staining in some tissue |
| Applications | Western blot : 1:500-1:1000 Flow cytometry : 1:10-1:50 (1x10e6 cells) Immunohistochemistry (FFPE) : 1:50-1:100 |
| Limitations | This Speedy protein A antibody is available for research use only. |
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SPDYA (speedy homolog A (Drosophila)) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.
The stated application concentrations are suggested starting points. Titration of the Speedy protein A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 147-175 from the human protein was used as the immunogen for the Speedy protein A antibody.
Aliquot the Speedy protein A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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