- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Somatostatin Antibody / Neuronostatin [clone SST/7200R] (V5022)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V5022-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
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V5022-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
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V5022SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | SST/7200R |
| Purity | Protein A/G affinity |
| UniProt | P61278 |
| Localization | Secreted |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT |
| Limitations | This Somatostatin antibody is available for research use only. |
|
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Somatostatin (SST) is a peptide hormone precursor encoded by the SST gene and widely recognized for suppressing the release of multiple secondary hormones through somatostatin receptor signaling. Somatostatin Antibody / Neuronostatin (clone SST/7200R) is a recombinant rabbit mAb suited to research focused on the SST precursor system, including mature somatostatin peptides and the related precursor-derived peptide neuronostatin. The SST gene gives rise to a single preprohormone that is processed into biologically active products, with somatostatin classically represented by 14-amino acid and 28-amino acid forms generated through alternate cleavage of the precursor.
Somatostatin is best known as an inhibitory neuroendocrine regulator. It is produced in the hypothalamus, pancreas, gastrointestinal tract, and additional neural and peripheral tissues, where it restrains secretion of growth hormone and influences release of other endocrine mediators. This broad inhibitory role makes Somatostatin antibody content relevant to investigators studying hormone control, neuroendocrine signaling, pancreatic islet biology, and gastrointestinal regulation. Because SST expression is distributed across nervous and endocrine compartments, an antibody against this target can support studies of peptide-producing cell populations as well as tissues in which somatostatin participates in local paracrine control.
Neuronostatin adds an important second dimension to SST biology. It is a 13-amino acid peptide derived from the somatostatin preprohormone and has been reported to show overlapping but distinct biology relative to somatostatin itself. Published work has described neuronostatin expression in hypothalamic neurons and pancreatic delta cells, and experimental studies indicate that it can regulate neuronal, cardiovascular, and metabolic functions through mechanisms that differ from classical somatostatin receptor signaling. Notably, neuronostatin does not appear to simply duplicate somatostatin activity, which is why Neuronostatin antibody and Somatostatin antibody search intent often overlap while still reflecting distinct research goals.
For antibody page SEO, this target benefits from coverage of both the hormone-centered and precursor-centered vocabulary surrounding SST. Researchers may search by gene symbol, mature peptide, precursor biology, or neuronostatin terminology depending on whether their work emphasizes endocrine inhibition, neuronal signaling, pancreatic islet regulation, or precursor peptide processing. A recombinant rabbit mAb such as clone SST/7200R therefore fits well within research programs examining somatostatin-producing cells, preprosomatostatin-derived peptides, and the broader biology of SST-driven regulatory pathways. This combined Somatostatin antibody and Neuronostatin antibody positioning helps the page capture both classic somatostatin research traffic and newer interest in neuronostatin-related signaling.
Optimal dilution of the Somatostatin antibody should be determined by the researcher.
A recombinant fragment of human protein was used as the immunogen for the Somatostatin antibody.
Aliquot the Somatostatin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Somatostatin antibody, Preprosomatostatin antibody, SST antibody, Neuronostatin peptide antibody, Somatostatin precursor antibody
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