- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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SOD3 is a member of the superoxide dismutase(SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. This protein is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.
Titration of the SOD3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 7-36 from the human protein was used as the immunogen for this SOD3 antibody.
Aliquot the SOD3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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