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Home >> Antibodies >> SMAD5 Antibody

SMAD5 Antibody (RQ5953)

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  Catalog No Formulation Size Price (USD)  
Image RQ5953 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 439
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Western blot testing of 1) rat liver and 2) mouse liver lysate with SMAD5 antibody. Expected molecular weight: 52~60 kDa.
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Western blot testing of 1) rat liver and 2) mouse liver lysate with SMAD5 antibody. Expected molecular weight: 52~60 kDa.
Western blot testing of 1) human HeLa, 2) human HepG2, 3) human 293T, 4) monkey COS-7 and 5) human Caco-2 cell lysate with SMAD5 antibody. Expected molecular weight: 52~60 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat, Monkey
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q99717
Localization Nuclear, cytoplasmic
Applications Western Blot : 0.5-1ug/ml
Limitations This SMAD5 antibody is available for research use only.
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Description

Mothers against decapentaplegic homolog 5 also known as SMAD5 is a protein that in humans is encoded by the SMAD5 gene. It is mapped to 5q31.1. The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.

Application Notes

Optimal dilution of the SMAD5 antibody should be determined by the researcher.

Immunogen

Amino acids QNATFPDSFHQPNNTPFPLSPN from the human protein were used as the immunogen for the SMAD5 antibody.

Storage

After reconstitution, the SMAD5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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