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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity). May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. [UniProt]
Titration of the Smad1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This Smad1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 154-187 amino acids from the central region of mouse Smad1.
Aliquot the Smad1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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