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Home >> Antibodies >> SLC25A19 Antibody

SLC25A19 Antibody (RQ6117)

  Catalog No Formulation Size Price (USD)  
Image RQ6117 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 359
Western blot testing of human 1) HEK293, 2) PC-3 and 3) MCF7 lysate with SLC25A19 antibody. Predicted molecular weight ~41 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt Q9HC21
Applications Western blot : 1-2ug/ml
Limitations This SLC25A19 antibody is available for research use only.
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Description

Mitochondrial thiamine pyrophosphate carrier is a protein that in humans is encoded by the SLC25A19 gene. This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

Application Notes

Optimal dilution of the SLC25A19 antibody should be determined by the researcher.

Immunogen

Amino acids PFDVIKIRFQLQHERL from the human protein were used as the immunogen for the SLC25A19 antibody.

Storage

After reconstitution, the SLC25A19 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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