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Home >> Antibodies >> SLC10A1 Antibody / NTCP

SLC10A1 Antibody / NTCP (RQ6905)

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  Catalog No Formulation Size Price (USD)  
Image RQ6905 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) monkey COS-7, 2) human HCCP, 3) rat liver and 4) mouse liver tissue lysate with SLC10A1 antibody. Expected molecular weight: 38~45 kDa.
Western blot testing of 1) monkey COS-7, 2) human HCCP, 3) rat liver and 4) mouse liver tissue lysate with SLC10A1 antibody. Expected molecular weight: 38~45 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat, Monkey
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q14973
Applications Western blot : 1-2ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This SLC10A1 antibody is available for research use only.
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Description

Sodium/bile acid cotransporter also known as the Na+-taurocholate cotransporting polypeptide (NTCP) or liver bile acid transporter (LBAT) is a protein that in humans is encoded by the SLC10A1 (solute carrier family 10 member 1) gene. The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis.

Application Notes

Optimal dilution of the SLC10A1 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids L137-E328) was used as the immunogen for the SLC10A1 antibody.

Storage

After reconstitution, the SLC10A1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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