SIRT5 Antibody / NAD-Dependent Deacylase Antibody (F49521)

SIRT5 Antibody Jurkat Cell WB. Western blot analysis of Jurkat cell lysate detected a distinct SIRT5 immunoreactive band at approximately 30 kDa, consistent with the expected molecular weight of the mature mitochondrial protein following cleavage of its N-terminal targeting sequence. This SIRT5 Antibody, a NAD-Dependent Deacylase Antibody, is suitable for detecting endogenous SIRT5 in studies of mitochondrial metabolism, lysine deacylation, protein acylation and cellular energy homeostasis.

SIRT5 Antibody Human Hepatocarcinoma IHC. Immunohistochemical staining of FFPE human hepatocarcinoma tissue demonstrated moderate to strong SIRT5 expression with predominantly cytoplasmic staining in tumor cells and weaker nuclear staining in a subset of cells. Heat-induced epitope retrieval was performed prior to immunostaining with HRP-DAB detection. The staining pattern is consistent with the predominantly mitochondrial localization of this NAD-Dependent Deacylase, which regulates mitochondrial metabolism and protein acylation. This SIRT5 Antibody, a NAD-Dependent Deacylase Antibody, is suitable for immunohistochemical studies of metabolic regulation, mitochondrial function and liver cancer biology.