- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
SIRT3 Antibody (F49520)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F49520-0.2ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.2 ml | 399 | |
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F49520-0.05ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.05 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Hamster |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | Q8R104 |
| Applications | Western blot : 1:1000 IHC (Paraffin) : 1:50-1:100 |
| Limitations | This SIRT3 antibody is available for research use only. |
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SIRT3 is an NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. [UniProt]
The stated application concentrations are suggested starting points. Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 304-334 from the mouse protein was used as the immunogen for this SIRT3 antibody.
Store at 4oC for up to one month. For long term, aliquot the SIRT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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