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Home >> Antibodies >> SIRT3 Antibody

SIRT3 Antibody (F43965)

  Catalog No Formulation Size Price (USD)  
Image F43965-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F43965-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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SIRT3 antibody western blot analysis in MDA-MB453 lysate. Predicted molecular weight: 44/28 kDa (full/processed)
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NTG7
Applications Western blot : 1:1000
Limitations This SIRT3 antibody is available for research use only.
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Description

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Application Notes

Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 56-84 from the human protein was used as the immunogen for this SIRT3 antibody.

Storage

Aliquot the SIRT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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