- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
SHISA7 Antibody (RQ6155)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ6155 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Affinity purified |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide |
| UniProt | A6NL88 |
| Applications | Western blot : 1-2ug/ml Direct ELISA : 0.1-0.5ug/ml |
| Limitations | This SHISA7 antibody is available for research use only. |
|
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Shisa7, a single-passing transmembrane protein, localizes at GABAergic inhibitory synapses and interacts with GABA-A receptors. Shisa7 controlled receptor abundance at synapses and sped up the channel deactivation kinetics. Shisa7 also potently enhanced the action of diazepam, a classic benzodiazepine, on GABA-A receptors. Genetic deletion of Shisa7 selectively impaired GABAergic transmission and diminished the effects of diazepam in mic
Optimal dilution of the SHISA7 antibody should be determined by the researcher.
A human recombinant partial protein (amino acids Y308-E535) was used as the immunogen for the SHISA7 antibody.
After reconstitution, the SHISA7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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