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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.
Optimal dilution of the SFTPD antibody should be determined by the researcher.
A portion of amino acids 241-336 was used as the immunogen for the SFTPD antibody.
Aliquot the SFTPD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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