- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
SEZ6L Antibody / Tumor-Associated Transmembrane Protein Antibody (RQ5836)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ5836 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 449 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Antigen affinity purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Affinity purified |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| UniProt | Q9BYH1 |
| Applications | Western Blot : 0.5-1ug/ml Immunofluorescence : 2-4ug/ml Flow Cytometry : 1-3ug/million cells Direct ELISA : 0.1-0.5ug/ml |
| Limitations | This SEZ6L Antibody / Tumor-Associated Transmembrane Protein Antibody is available for research use only. |
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Seizure related 6 homolog like (SEZ6L) is a type I transmembrane protein belonging to the seizure-related protein family involved in extracellular signaling, cell interaction pathways, and membrane-associated regulatory processes. SEZ6L Antibody / Tumor-Associated Transmembrane Protein Antibody recognizes a membrane-associated glycoprotein characterized by extracellular complement C1r/C1s, Uegf, and Bmp1 (CUB) domains together with Sushi/CCP protein interaction motifs that contribute to intercellular communication and signaling-associated functions.
SEZ6L antibody, also referred to as seizure related 6 homolog like antibody and SEZ6-like protein antibody in the literature, is useful for investigating membrane-associated signaling pathways, neuronal-associated biology, and tumor-related cellular interaction mechanisms. SEZ6L has attracted increasing interest in studies examining cancer-associated expression patterns and transmembrane signaling networks linked to epithelial tumor progression.
SEZ6L is primarily localized to the plasma membrane and secretory pathway-associated cellular compartments where it may participate in extracellular protein interactions and cell surface communication pathways. Members of the SEZ6 protein family are strongly associated with neuronal development and synaptic biology, although SEZ6L expression has additionally been reported in multiple non-neuronal tissues and tumor-associated cellular populations.
In cancer biology research, elevated SEZ6L expression has been described in lung adenocarcinoma and additional epithelial malignancies. The protein has been investigated as a potential tumor-associated biomarker linked to cellular proliferation, migration, extracellular signaling adaptation, and cancer-associated membrane protein regulation. Because SEZ6L is membrane-associated and exposed to extracellular interaction networks, it has also attracted interest in studies examining therapeutic targeting strategies and tumor-associated cell surface biology.
SEZ6L contains multiple extracellular protein interaction domains that may contribute to signaling complex formation, receptor-associated communication, and membrane trafficking-associated processes. Although the precise biologic functions of SEZ6L remain incompletely characterized, available evidence supports involvement in cell interaction pathways and extracellular signaling regulation associated with both neuronal and tumor-associated cellular systems.
Immunohistochemistry and immunofluorescence staining with SEZ6L antibodies may demonstrate membranous, cytoplasmic, and vesicular localization patterns depending on cell type and biologic context. Western blot analysis typically identifies SEZ6L as a relatively high molecular weight glycoprotein with variable migration patterns that may reflect glycosylation state and post-translational processing-associated modification.
The growing interest in SEZ6L within tumor biology and membrane signaling research supports the utility of SEZ6L antibodies for investigating transmembrane signaling pathways, extracellular interaction networks, and cancer-associated membrane protein biology. The protein's association with both neuronal systems and epithelial tumor-associated signaling further contributes to its emerging relevance in translational and cell biology research applications.
Together, the available literature and biologic characterization support the use of SEZ6L antibody for investigating tumor-associated transmembrane signaling pathways, extracellular protein interaction biology, and membrane-associated regulatory mechanisms.
Explore additional Cancer Antibodies targeting tumor-associated transmembrane proteins, extracellular signaling regulators, and membrane-associated cellular interaction pathways.
Optimal dilution of the SEZ6L Antibody / Tumor-Associated Transmembrane Protein Antibody should be determined by the researcher.
Recombinant human protein (amino acids E662-E953) was used as the immunogen for the SEZ6L antibody.
After reconstitution, the SEZ6L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
SEZ6L antibody, seizure related 6 homolog like antibody, seizure-related protein antibody, transmembrane signaling protein antibody, SEZ6-like protein antibody
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