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Home >> Antibodies >> Sex Hormone Binding Globulin Antibody / SHBG

Sex Hormone Binding Globulin Antibody / SHBG [clone SHBG/8924] (V5419)

  Catalog No Formulation Size Price (USD)  
Image V5419-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5419-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5419SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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IHC staining of FFPE human testis tissue with Sex Hormone Binding Globulin antibody (clone SHBG/8924). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free Sex Hormone Binding Globulin antibody (clone SHBG/8924) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name SHBG/8924
Purity Protein A/G affinity
UniProt P04278
Localization Cytoplasm, Extracellular (Secreted)
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This Sex Hormone Binding Globulin antibody is available for research use only.
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Description

Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.

Application Notes

Optimal dilution of the Sex Hormone Binding Globulin antibody should be determined by the researcher.

Immunogen

Recombinant full-length human Sex Hormone Binding Globulin protein was used as the immunogen for the Sex Hormone Binding Globulin antibody.

Storage

Aliquot the Sex Hormone Binding Globulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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