- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
SERPINB2 is also known as PAI or PAI2. It is a coagulation factor that inactivates tPA and Urokinase. It is present in most cells, especially monocytes/macrophages. The protein exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosisduring pregnancy. The majority of expressed SERPINB2 remains unsecreted due to the presence of an inefficient internal signal peptide.
The stated application concentrations are suggested starting amounts. Titration of the SERPINB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Human partial recombinant protein (AA 1-180) was used as the immunogen for this SERPINB2 antibody.
After reconstitution, the SERPINB2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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