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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation. [UniProt]
For highly specific detection of SERBP1-associated RNA regulatory signaling pathways, see our SERBP1 Antibody / mRNA Binding Protein Antibody page featuring clone SERBP1/3491 with WB, IHC, and HuProt(TM) microarray specificity validation data.
The stated application concentrations are suggested starting points. Titration of the SERBP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
A recombinant human partial protein corresponding to amino acids 3-139 was used as the immunogen for the SERBP1 antibody.
Store the SERBP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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