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Home >> Antibodies >> Semaphorin-4D Antibody / SEMA4D / CD100

Semaphorin-4D Antibody / SEMA4D / CD100 [clone SEMA4D/933] (V2453)

  Catalog No Formulation Size Price (USD)  
Image V2453-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V2453-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V2453SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name SEMA4D/933
Purity Protein G affinity chromatography
UniProt Q92854
Localization Cell surface
Applications Flow cytometry : 0.5-1ug/10^6 cells
Immunofluorescence : 0.5-1ug/ml
Limitations This Semaphorin-4D antibody is available for research use only.
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Description

Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Application Notes

Optimal dilution of the Semaphorin-4D antibody should be determined by the researcher.

Immunogen

Human recombinant protein was used as the immunogen for the Semaphorin-4D antibody.

Storage

Store the Semaphorin-4D antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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