• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> SDHA Antibody

SDHA Antibody (R30807)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image R30807 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
Bulk quote request
Western blot testing of 1) rat brain, 2) rat kidney, 3) rat spleen, 4) rat liver, 5) mouse brain, 6) mouse kidney and 7) mouse liver tissue lysate with SDHA antibody. Predicted molecular weight ~73 kDa.
›
Western blot testing of 1) rat brain, 2) rat kidney, 3) rat spleen, 4) rat liver, 5) mouse brain, 6) mouse kidney and 7) mouse liver tissue lysate with SDHA antibody. Predicted molecular weight ~73 kDa.
Western blot testing of human 1) HeLa, 2) HepG2, 3) HT1080, 4) Jurkat, 5) 293T, 6) monkey COS-7, 7) human ThP-1 and 8) human SiHa cell lysate with SDHA antibody. Predicted molecular weight ~73 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat, Monkey
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P31040
Applications Western blot : 0.5-1ug/ml
Limitations This SDHA antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

  • Applications : IHC-P
    Reactivity : Human
  • Applications : IHC-P
    Reactivity : Human
  • Applications : IHC-P
    Reactivity : Human
  • Applications : IHC-P
    Reactivity : Human
  • Applications : IHC, WB, ELISA
    Reactivity : Human
    Pred. Reactivity : Rat, Xenopus
  • Applications : WB
    Reactivity : Human, Mouse, Rat
  • Applications : WB, IF, FACS
    Reactivity : Human, Mouse, Rat

Description

Succinate dehydrogenase complex, subunit a, flavoprotein is a protein that in humans is encoded by the SDHA gene. The gene that codes for the protein is nuclear, even though the protein is located in the inner membrane of the mitochondria. Heterozygous carriers of an SDHA mutation do not develop paragangliomas as has been seen for mutations in the other subunits. In vitro functional expression studies in the yeast homolog showed that the mutation resulted in a loss of SDH activity and rendered the mutant protein more susceptible to proteolysis. The findings indicated that SDHA, like other SDH subunits, can act as a tumor suppressor gene.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the SDHA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the N-terminus of human SDHA (NMEEDNWRWHFYDTVK) was used as the immunogen for this SDHA antibody (100% homologous in human, mouse and rat).

Storage

After reconstitution, the SDHA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Related Products

   1.   View all SDHA antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.