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Home >> Antibodies >> Scurfin Antibody / FOXP3

Scurfin Antibody / FOXP3 (RQ7764)

  Catalog No Formulation Size Price (USD)  
Image RQ7764 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human 1) 293T, 2) HeLa, 3) A375 and 4) MCF7 cell lysate with Scurfin antibody. Predicted molecular weight ~47 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q9BZS1
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This Scurfin antibody is available for research use only.
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Description

FOXP3 (forkhead box P3), also called Scurfin, is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome (specifically, Xp11.23). A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription.

Application Notes

Optimal dilution of the Scurfin antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids R27-R337) was used as the immunogen for the Scurfin antibody.

Storage

After reconstitution, the Scurfin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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